New Study Asks: What is the optimal amount of activity vs exercise?

This is an old story, but one with confusing data. The U.S. Department of Health and Human Services’ current physical activity guidelines recommend as little as 150 minutes of moderate physical activity [MPA aka simple “activity”] per week (to which it has recently added 75 minutes of vigorous physical activity [VPA aka exercise] or an equivalent combination of both. Given that almost anything counts as MPA ie “activity” eg going for a walk, doing housework…..150mins is not very much (it’s 21mins per day). VPA ie “exercise” includes jogging, cycling, swimming etc and that would be as little as 10mins per day.

This is also an area with a large number of beliefs, which might well be myths; or at least uncertainties and these are:

Guideline rates of exercise are enough

Too much exercise is bad for you, so only do a little

Too much VPA is definitely bad for you, so only do a little

If you do MPA, then you don’t need any VPA

Fortunately a new study published in Circulation has examined all these, and the results are not as expected.

This study combined 2 large prospective US cohorts (Nurses’ Health Study and Health Professionals Follow-up Study, 1988–2018) in order to examine 116,221 adults using a self-reported questionnaire repeated up to 15 times beginning in 1986 and continuing for 30 years of follow up!

 

Myth 1: Guideline rates of exercise are enough

OK, Let us examine myth 1, that doing the recommended amount is enough.

During 2984545 person-years of follow-up (median, 26 years) there were 47596 deaths.

In terms of long-term leisure-time MPA, compared with those with no MPA, participants who met guidelines had 20% lower all-cause mortality and 22% lower CVD mortality

 Compared with those with no VPA, participants who met the long-term VPA guidelines (75–149 min/wk of VPA) had 19% lower all-cause mortality and 31% lower CVD mortality

So far, so good, but if you did the optimal amount of MPA (500mins) you could lower your risk to 0.69 (ie 31% lower vs 20% above); and if you did the optimal amount of VPA ( 400mins) you could lower your risk to 0.73 (ie 27% lower vs 19% above)

 

Myth 2: Too much exercise is bad for you, so only do a little

The research also showed a dose-response relationship, the more MPA you did, the better. This is shown on the the following graph, at 600 mins MPA (thats 10hr per week or 1.4hrs / day) you get 32% risk reduction

Now a thought experiment……given the line becomes almost linear after 500mins, what amount of time “active” would give 50% risk reduction??

Risk of Mortality vs Active time Per Day

32% risk reduction = 1.4 hrs per day

50% risk reduction = 2.6 hrs per day

75% risk reduction = 4.7hrs per day

99% risk reduction = 6.6 hrs per day!

 

Myth 3: Too much exercise (VPA) is definitely bad for you, so only do a little

This is interesting. The research also showed a dose-response relationship in terms of VPA / exercise, the more VPA you did, the better but there was a plateau, with not much benefit above 400mins VPA/week *but no evidence of harm either*

So, if you had a choice, and based on this data, I would say you should not limit your VPA for fears of “no benefit”.

 

Myth 4: If you do MPA, then you don’t need any VPA

The researchers also looked at the *combination* of activity vs exercise . Here are the results. Each block at the bottom is a band of activity (MPA) and each coloured dot is a band of exercise (VPA)

What this shows is; if you are inactive, you get a massive benefit of any duration of true exercise especially 150mins/week or more (that is only  21mins per day)

However if you were doing roughly an hour a day or “activity” then the benefits of exercise were not as clear BUT this was confounded by large uncertainty in those doing no VPA (likely due to sample size).

 

Conclusion: Are Guidelines Correct?

What this study shows is that if you do the minimum qualifying activity and exercise US guidance 150 minutes MPA “activity” per week and 75 minutes of VPA aka exercise you get about 30% risk reduction.

BUT by adding more MPA or more VPA you could get 45% risk reduction.

 

Citation

https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.121.058162?download=true

Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults